Serum albumin is the most plentiful
protein in blood plasma and is made by liver. Since serum albumin
is so common in the blood and so easy to purify, it was one
of the first proteins to be studied by scientists. Albumin is
a protein made by the liver. A serum albumin test measures the
amount of this protein in the clear liquid portion of the blood
helps move many small molecules through the blood, including
bilirubin, calcium, progesterone, and medications. It plays
an important role in keeping the fluid from the blood from
leaking out into the tissues.
albumin is made by the liver, decreased serum albumin may
be a sign of liver disease. It can also result from kidney
disease, which allows albumin to escape into the urine. Decreased
albumin may also be explained by malnutrition or a low protein
When the serum albumin test is done?
As a routine part of investigation done in a "bone
and joint" panel
determine if a patient has liver disease or kidney disease,
or if the body is not absorbing enough protein
conditions under which the test may be performed:
What will the results of serum albumin test tell me?
range: 3.4 - 5.4 grams per deciliter (g/dL)
Higher than normal levels of serum albumin in the blood are
excess (can result from taking medications with cortisone
effect, the adrenal gland overproducing cortisol, or a tumor
that produces extra cortisol like compounds)
(in born / present at birth)
Lower than normal levels of serum albumin in the blood are
disease (for example, hepatitis, cirrhosis, or hepatocellular
syndromes (for example, Crohn's disease, sprue, or Whipple's
albumin will be decreased during pregnancy.
How serum albumin blood test is done?
A blood sample is needed from one of your veins in a usual
way. The blood sample is placed in a machine called a centrifuge,
which spins and separates the cells from the liquid part of
the blood (the serum).
there any precautions for the test?
There are certain drugs that may interfere with your serum
albumin test results. Your health care provider will instruct
you, if necessary, to discontinue drugs that may interfere
with the test.
that can increase albumin measurements include anabolic steroids,
androgens, growth hormone, and insulin. Also, if you are receiving
large amounts of intravenous fluids, the results of this test
may be inaccurate. Therefore, let your health care provider
know of the same before you perform the test.